Mechanical Blood Trauma in Assisted Circulation: Sublethal RBC Damage Preceding Hemolysis
نویسندگان
چکیده
منابع مشابه
Effects of Suspension Osmolarity on Rbc Mechanical Properties and Shear Induced Hemolysis
INTRODUCTION Storage of human red blood cells (RBCs) began around 1910 when the anticoagulant properties of citrate were discovered. Over the last century, RBC storage techniques were improved so patients can receive healthy RBCs after longer storage periods. Today, about 80 million transfusions per year are performed worldwide [1,2]. Many parameters, such as temperature and nutrient concentrat...
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BACKGROUND Almost 2 percent of murine blood red blood cells (RBCs) are destroyed each day and are replaced by fresh RBCs generated through the process of erythropoiesis. RBCs to be destroyed are phagocytosed by macrophages in the reticuloendothelial system, especially in the spleen. CD47 molecules on RBCs may regulate the susceptibility of RBC to destruction by phagocytosis because its recognit...
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ژورنال
عنوان ژورنال: The International Journal of Artificial Organs
سال: 2016
ISSN: 0391-3988,1724-6040
DOI: 10.5301/ijao.5000478